Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.64 |
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30539520 | 0.83 | LOXL2 (0.60) | LOXL2AHRHRH3HRH4AOC3 | |
| SCHEMBL2970418 | 0.83 | LOXL2 (0.60) | LOXL2AHRHRH3HRH4AOC3 | |
| SCHEMBL28338445 | 0.82 | LOXL2 (0.69) | LOXL2AHRHRH3HRH4AOC3 | |
| SCHEMBL29403791 | 0.82 | LOXL2 (0.69) | LOXL2AHRHRH3HRH4AOC3 | |
| SCHEMBL7169246 | 0.82 | LOXL2 (0.69) | LOXL2AHRHRH3HRH4AOC3 | |
| SCHEMBL401081 | 0.82 | LOXL2 (0.69) | LOXL2AHRHRH3HRH4AOC3 | |
| SCHEMBL31059889 | 0.82 | LOXL2 (0.69) | LOXL2AHRHRH3HRH4AOC3 | |
| SCHEMBL28545346 | 0.81 | LOXL2 (0.62) | LOXL2AHRHRH3HRH4AOC3 | |
| SCHEMBL3272996 | 0.80 | LOXL2 (0.56) | LOXL2AHRHRH3HRH4MTNR1A | |
| SCHEMBL28335219 | 0.80 | LOXL2 (0.67) | LOXL2AHRHRH3AOC3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230119640-A1 | ANTIBACTERIAL HYDROPHILIC COMPOUND | SHENZHEN UNIVERSITY (CN) | 2023-04-20 | — | — | US | disclosed |
| US-11503828-B2 | Antibacterial hydrophilic compound and use thereof | SHENZHEN UNIVERSITY (CN) | 2022-11-22 | — | — | US | disclosed |
| US-20200093124-A1 | ANTIBACTERIAL HYDROPHILIC COMPOUND AND USE THEREOF | SHENZHEN UNIVERSITY (CN) | 2020-03-26 | — | — | US | disclosed |
| CN-110105338-A | 6 '-replace amine formyl benzimidazole -4- substituent methyl indole derivatives | 东华大学 | 2019-08-09 | — | — | CN | disclosed |
| CN-103435605-B | A kind of morpholine class tetrazotized zole compound and its preparation method and application | DONGHUA UNIVERSITY (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-103435605-B | A kind of morpholine class tetrazotized zole compound and its preparation method and application | DONGHUA UNIVERSITY (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-102796083-B | Assorted spirocyclic ketone N-Phenylindole compounds, its preparation method and application | CHEN ZHILONG (CN) | 2015-09-30 | — | — | CN | disclosed |
| US-20150057433-A1 | PREPARATION OF FUNCTIONALIZED POLYPEPTIDES, PEPTIDES, AND PROTEINS BY ALKYLATION OF THIOETHER GROUPS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-26 | — | — | US | disclosed |
| CN-103145697-B | Nitrobenzimidazole compound, preparation method and application thereof | UNIV DONGHUA | 2015-02-25 | — | — | CN | disclosed |
| CN-103145697-B | Nitrobenzimidazole compound, preparation method and application thereof | UNIV DONGHUA | 2015-02-25 | — | — | CN | disclosed |
| EP-1660484-A1 | METHYL INDOLES AND METHYL PYRROLOPYRIDINES AS ALPHA-1 ADRENERGIC AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-05-31 | — | — | EP | disclosed |
| US-6979696-B2 | Method for detecting a gram-negative bacterial autoinducer molecule | ROCHE PALO ALTO LLC (US) | 2005-12-27 | — | — | US | disclosed |
| WO-2004099189-A1 | METHYL INDOLES AND METHYL PYRROLOPYRIDINES AS ALPH-1 ADRENERGIC AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-11-18 | — | — | WO | disclosed |
| US-20040224973-A1 | Substituted indoles as alpha-1 agonists | ROCHE PALO ALTO LLC | 2004-11-11 | — | — | US | disclosed |
| US-6376253-B1 | CULTIVATION OF A MICROBIAL CULTURE CONTAINING ISOTOPICALLY LABELED AMINO ACIDS | MARTEK BIOSCIENCES CORPORATION | 2002-04-23 | — | — | US | disclosed |
| US-6340578-B1 | HIGH SPEED DETERMINATION OF THREE-DIMENSIONAL STRUCTURE USING ISOTOPES; POLYPEPTIDE BIOSYNTHESIS | MARTEK BIOSCIENCES CORPORATION | 2002-01-22 | — | — | US | disclosed |
| US-6335196-B1 | NUTRIENT BROTH; FOR USE IN THE PROPAGATION OF BACTERIAL, YEAST, MAMMALIAN OR INSECT CELL CULTURES | MARTEK BIOSCIENCES CORP. | 2002-01-01 | — | — | US | disclosed |
| US-6111066-A | PEPTIDES SUBSTITUTED WITH CARBON, NITROGEN AND HYDROGEN ISOTOPES; FOR THREE DIMENSIONAL NUCLEAR MAGNETIC RESONANCE STRUCTURE DETERMINATION; PRODUCED BY CELL CULTURE | MARTEK BIOSCIENCES CORPORATION (US) | 2000-08-29 | — | — | US | disclosed |
| EP-1009725-A1 | 13C,15N,2H LABELED PROTEINS FOR NMR STRUCTURE DETERMINATIONS AND THEIR PREPARATION | MARTEK BIOSCIENCES CORPORATION (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999011589-A1 | 13C, 15N, 2H LABELED PROTEINS FOR NMR STRUCTURE DETERMINATIONS AND THEIR PREPARATION | MARTEK BIOSCIENCES CORPORATION (US) | 1999-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224973-A1 | Substituted indoles as alpha-1 agonists | ADRA1A, ADRB1, ADRA1D | LOXL2 2021/4885AHR 210/4885HRH3 269/4885 |
| US-20200093124-A1 | ANTIBACTERIAL HYDROPHILIC COMPOUND AND USE THEREOF | HIRA, NOD2, HIRIP3 | LOXL2 2708/4885AHR 640/4885HRH3 28/4885 |
| US-11503828-B2 | Antibacterial hydrophilic compound and use thereof | HIRA, NOD2, HIRIP3 | LOXL2 2708/4885AHR 640/4885HRH3 28/4885 |
| US-20150057433-A1 | PREPARATION OF FUNCTIONALIZED POLYPEPTIDES, PEPTIDES, AND PROTEINS BY ALKYLATION OF THIOETHER GROUPS | PTMS, TMT1A, PTMA | LOXL2 3543/4885AHR 4373/4885HRH3 3659/4885 |
| US-20230119640-A1 | ANTIBACTERIAL HYDROPHILIC COMPOUND | HIRA, NOD2, CHLSN | LOXL2 3034/4885AHR 1164/4885HRH3 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.