Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863154 | 0.93 | MAPT (0.45) | MAPTP2RX7LMNATSHRL3MBTL1 | |
| SCHEMBL2852524 | 0.92 | TAAR1 (0.45) | TRPV1LTA4HEPHX2MAPTLMNA | |
| SCHEMBL2861752 | 0.89 | MAPT (0.43) | MAPTP2RX7LMNATSHRL3MBTL1 | |
| SCHEMBL2854309 | 0.89 | MAPT (0.42) | MAPTP2RX7LMNATSHRL3MBTL1 | |
| SCHEMBL2850857 | 0.89 | TP53 (0.46) | MAPTP2RX7LMNATSHRL3MBTL1 | |
| SCHEMBL2860458 | 0.89 | TP53 (0.46) | MAPTP2RX7LMNATSHRL3MBTL1 | |
| SCHEMBL2854346 | 0.88 | MAPT (0.52) | MAPTP2RX7LMNAPOLBTSHR | |
| SCHEMBL2856562 | 0.88 | MAPT (0.48) | LTA4HEPHX2MAPTP2RX7LMNA | |
| SCHEMBL2860669 | 0.84 | TAAR1 (0.46) | MAPTP2RX7LMNATP53 | |
| SCHEMBL2855493 | 0.84 | P2RX7 (0.48) | TRPV1MAPTP2RX7NR3C1SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |