Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856388 | 0.93 | TRPV1 (0.51) | SMN1; SMN2L3MBTL1ALDH1A1HTTKMT2A | |
| SCHEMBL2848518 | 0.92 | ALDH1A1 (0.58) | SMN1; SMN2L3MBTL1ALDH1A1HTTMAPK1 | |
| SCHEMBL2850427 | 0.91 | SMN1; SMN2 (0.60) | SMN1; SMN2L3MBTL1ALDH1A1HTTKMT2A | |
| SCHEMBL2863326 | 0.91 | TP53 (0.53) | SMN1; SMN2ALDH1A1HTTKMT2ATP53 | |
| SCHEMBL2862835 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1HTTKMT2ARAB9A | |
| SCHEMBL2851002 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1ALDH1A1HTTMAPK1 | |
| SCHEMBL2850129 | 0.86 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1HTTMAPK1KMT2A | |
| SCHEMBL2852370 | 0.83 | ALDH1A1 (0.52) | SMN1; SMN2L3MBTL1ALDH1A1HTTMAPK1 | |
| SCHEMBL2857977 | 0.83 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1HTTMAPK1KMT2A | |
| SCHEMBL2852241 | 0.83 | MAPK1 (0.53) | SMN1; SMN2MAPK1P2RX7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |