Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848480 | 0.91 | ALDH1A1 (0.61) | SMN1; SMN2L3MBTL1ALDH1A1HTTMAPK1 | |
| SCHEMBL2857766 | 0.90 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1HTTKMT2AHPGD | |
| SCHEMBL2854686 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1ALDH1A1HTTMAPK1 | |
| SCHEMBL2863134 | 0.86 | CCR1 (0.48) | SMN1; SMN2ALDH1A1MAPK1SMOHPGD | |
| SCHEMBL2857180 | 0.81 | NPSR1 (0.53) | MAPK1RAB9APOLBSMOTP53 | |
| SCHEMBL2853267 | 0.81 | HPGD (0.55) | SMN1; SMN2ALDH1A1MAPK1RAB9ASMO | |
| SCHEMBL2853344 | 0.81 | HPGD (0.55) | SMN1; SMN2ALDH1A1MAPK1RAB9AKMT2A | |
| SCHEMBL2854802 | 0.81 | LMNA (0.48) | L3MBTL1ALDH1A1KMT2APOLBTP53 | |
| SCHEMBL2856388 | 0.80 | TRPV1 (0.51) | SMN1; SMN2L3MBTL1ALDH1A1HTTKMT2A | |
| SCHEMBL2863326 | 0.80 | TP53 (0.53) | SMN1; SMN2ALDH1A1HTTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |