Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854686 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL2856388 | 0.89 | TRPV1 (0.51) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL2848518 | 0.88 | ALDH1A1 (0.58) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL2863326 | 0.87 | TP53 (0.53) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2850427 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL2854333 | 0.86 | RAB9A (0.52) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL2856212 | 0.85 | CCR1 (0.47) | SMN1; SMN2MAPTCCR1NPC1RAB9A | |
| SCHEMBL2854244 | 0.84 | ACHE (0.52) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL2858076 | 0.84 | MAPT (0.56) | MAPTCCR1NPC1RAB9ANPSR1 | |
| SCHEMBL2861197 | 0.83 | CCR1 (0.51) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |