Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | MST1R | Q04912 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3478457 | 0.83 | SCN9A (0.49) | EDNRASCN9A | |
| SCHEMBL28547668 | 0.83 | EDNRA (0.47) | EDNRALTA4HKDM4EALDH1A1HPGD | |
| SCHEMBL7950052 | 0.83 | EDNRA (0.47) | EDNRALTA4HKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15518348 | 0.81 | EDNRA (0.46) | EDNRALTA4HKDM4EALDH1A1KMT2A | |
| SCHEMBL4021097 | 0.79 | EDNRA (0.44) | EDNRALTA4HKDM4EALDH1A1KMT2A | |
| SCHEMBL995326 | 0.76 | LTA4H (0.55) | LTA4HKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8796816 | 0.75 | IDO1 (0.43) | EDNRAPTGS2HSD11B1KDM4EALDH1A1 | |
| SCHEMBL1271460 | 0.75 | LTA4H (0.57) | EDNRALTA4HPTGS2GLO1KDM4E | |
| Sulfamide SCHEMBL28034979 | 0.74 | RAB9A (0.51) | EDNRALTA4HKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10623296 | 0.74 | EDNRA (0.49) | EDNRALTA4HKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339428-A1 | INHALATION OF NITRIC OXIDE | AGA AB (SE) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002040052-A1 | INHALATION OF NITRIC OXIDE | AGA AB (SE) | 2002-05-23 | — | — | WO | disclosed |