Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010785 | 0.81 | NR4A1 (0.53) | KDM4EHPGDL3MBTL1NR4A1NR4A2 | |
| SCHEMBL20398171 | 0.79 | L3MBTL1 (0.52) | KDM4EHPGDL3MBTL1NR4A1NR4A2 | |
| SCHEMBL3282190 | 0.78 | PTPN1 (0.62) | KDM4EHPGDL3MBTL1NR4A1NR4A2 | |
| SCHEMBL758421 | 0.78 | KDM4E (0.50) | KDM4EHPGDL3MBTL1NR4A1NR4A2 | |
| SCHEMBL7239901 | 0.77 | GPR52 (0.49) | KDM4EHPGDL3MBTL1NR4A1NR4A2 | |
| SCHEMBL13963143 | 0.77 | PTPN1 (0.61) | KDM4EHPGDL3MBTL1NR4A1NR4A2 | |
| SCHEMBL2098307 | 0.77 | PTK2B (0.50) | KDM4EHPGDL3MBTL1NR4A1NR4A2 | |
| SCHEMBL10581635 | 0.77 | PTK2B (0.50) | KDM4EHPGDL3MBTL1NR4A1NR4A2 | |
| SCHEMBL9385109 | 0.77 | PTK2B (0.50) | KDM4EHPGDL3MBTL1NR4A1NR4A2 | |
| SCHEMBL9562390 | 0.76 | NR4A1 (0.58) | KDM4EHPGDL3MBTL1NR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978216-B | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-111978216-A | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2020-11-24 | — | — | CN | disclosed |