SCHEMBL5010785

SCHEMBL5010785

c1ccc(C[C](c2cccc3ccccc23)c2cccc3ccccc23)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.53
NR4A2 P43354 1/20 0.53
NR4A3 Q92570 1/20 0.53
HPGD P15428 4/20 0.53
KDM4E B2RXH2 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
NR1H4 Q96RI1 1/20 0.50
GPR52 Q9Y2T5 1/20 0.47
PTPN1 P18031 1/20 0.47
CDC25B P30305 1/20 0.47
TDP1 Q9NUW8 3/20 0.45
MEN1 O00255 3/20 0.45
ALDH1A1 P00352 3/20 0.45
MAPT P10636 3/20 0.45
KMT2A Q03164 3/20 0.45
GMNN O75496 2/20 0.45
LMNA P02545 2/20 0.45
POLB P06746 2/20 0.45
MAPK1 P28482 2/20 0.45
BLM P54132 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3282190 0.81 PTPN1 (0.62) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL758421 0.81 KDM4E (0.50) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL28547802 0.81 KDM4E (0.50) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL5013873 0.80 TDP1 (0.58) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL7354117 0.78 KDM4E (0.48) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL7239901 0.77 GPR52 (0.49) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL3246864 0.75 NR4A1 (0.52) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL27405415 0.75 PTPN1 (0.66) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL5010784 0.74 TDP1 (0.56) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL29222012 0.74 HPGD (0.62) NR4A1NR4A2NR4A3HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207864-A1 Organosilanes, Process For Production of the Same, and Use Thereof SHARP KABUSHIKI KAISHA (JP) 2008-08-28 US disclosed