Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857987 | 0.94 | CNR1 (0.43) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2853063 | 0.93 | P2RX7 (0.48) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2854809 | 0.91 | HPGD (0.45) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2854705 | 0.90 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2858268 | 0.90 | P2RX7 (0.48) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2857936 | 0.89 | KDM4E (0.47) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2860131 | 0.88 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2854716 | 0.87 | MTNR1A (0.47) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2854509 | 0.86 | KDM4E (0.50) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2859861 | 0.86 | TAAR1 (0.51) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |