Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL28553014 | 0.97 | SLC7A5 (0.49) | SLC7A5SERPINE1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL731020 | 0.92 | SERPINE1 (0.51) | SLC7A5SERPINE1SMN1; SMN2LMNACYP1A2 | |
| Triethylene Glycol SCHEMBL11781871 | 0.86 | TDP1 (0.50) | SLC7A5SERPINE1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL731019 | 0.86 | TDP1 (0.50) | SLC7A5SERPINE1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL9123912 | 0.85 | SLC7A5 (0.49) | SLC7A5SERPINE1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL27892603 | 0.85 | CYP4A11 (0.59) | SLC7A5SERPINE1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL28388341 | 0.84 | SLC7A5 (0.45) | SLC7A5SERPINE1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL6736568 | 0.84 | SLC7A5 (0.59) | SLC7A5SERPINE1SMN1; SMN2LMNACYP4F2 | |
| Triethylene Glycol SCHEMBL11779885 | 0.83 | SLC7A5 (0.53) | SLC7A5SERPINE1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL14927377 | 0.82 | RAB9A (0.52) | SLC7A5SERPINE1SMN1; SMN2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112694423-A | Isophthalic acid diethylene glycol ester sulfonate solution and preparation method and application thereof | 东丽纤维研究所（中国）有限公司 | 2021-04-23 | — | — | CN | claimed |
| CN-112694423-A | Isophthalic acid diethylene glycol ester sulfonate solution and preparation method and application thereof | 东丽纤维研究所（中国）有限公司 | 2021-04-23 | — | — | CN | disclosed |