SCHEMBL28548638

SCHEMBL28548638

CCC(C(=O)O)C(=O)c1ccc(OC)cc1.O=C1c2ccccc2C(=O)N1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.52
GAA P10253 1/20 0.48
TP53 P04637 1/20 0.45
MAPT P10636 1/20 0.45
ALDH1A1 P00352 3/20 0.45
CYP1A2 P05177 2/20 0.45
TNF P01375 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MMP2 P08253 2/20 0.44
MMP9 P14780 2/20 0.44
MITF O75030 1/20 0.44
LMNA P02545 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HIF1A Q16665 1/20 0.44
KMT2A Q03164 1/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
NPSR1 Q6W5P4 2/20 0.43
CASP3 P42574 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2290396 0.84 ALDH1A1 (0.60) NPC1MAPTALDH1A1CYP1A2KMT2A
P-Anisic Acid SCHEMBL28548631 0.81 CA1 (0.62) NPC1GAAMAPTCYP1A2L3MBTL1
SCHEMBL28557976 0.81 AKR1C3 (0.54) NPC1GAAALDH1A1TNFMMP2
SCHEMBL5217775 0.78 GSK3B (0.56) ALDH1A1CYP1A2LMNASMN1; SMN2KMT2A
SCHEMBL28552099 0.76 PTGS2 (0.51) NPC1GAATP53ALDH1A1CYP1A2
SCHEMBL5215355 0.74 MAPT (0.52) NPC1MAPTALDH1A1CYP1A2L3MBTL1
SCHEMBL28560296 0.73 ALDH1A1 (0.56) ALDH1A1CYP1A2SMN1; SMN2KMT2ACASP3
SCHEMBL10427298 0.73 LMNA (0.72) NPC1GAATP53MAPTALDH1A1
SCHEMBL10427299 0.73 LMNA (0.72) NPC1GAATP53MAPTALDH1A1
SCHEMBL442090 0.72 MDM2 (0.59) NPC1MAPTALDH1A1L3MBTL1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112746289-B Synthesis method of alkyl borate compound 合肥工业大学 2021-11-09 CN disclosed
CN-112746289-A Synthesis method of alkyl borate compound 合肥工业大学 2021-05-04 CN disclosed