SCHEMBL3233199

SCHEMBL3233199

CCCCCCCCCCCCC(C)(CCCCCCCCCCCC)C(CO)(CO)CO

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
TSHR P16473 2/20 0.42
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
GGPS1 O95749 6/20 0.40
FDPS P14324 9/20 0.39
THRB P10828 1/20 0.38
CES2 O00748 1/20 0.38
LPAR1 Q92633 1/20 0.38
LPAR3 Q9UBY5 1/20 0.38
SMPD1 P17405 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28416994 0.90 ALDH1A1 (0.36) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL4527292 0.84 LMNA (0.40) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL22921051 0.83 LMNA (0.43) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL18938914 0.81 LMNA (0.34) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL2848772 0.80 LMNA (0.46) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL2854867 0.80 LMNA (0.46) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL2852624 0.80 LMNA (0.46) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL27285703 0.78 FDPS (0.45) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL7044918 0.77 LMNA (0.48) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL20873213 0.77 LMNA (0.48) LMNATSHRALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090004132-A1 Transfer resistant cosmetic composition with improved feel MOMENTIVE PERFORMANCE MATERIALS INC. 2009-01-01 US claimed
WO-2009002498-A2 TRANSFER RESISTANT COSMETIC COMPOSITION WITH IMPROVED FEEL MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-12-31 WO claimed
EP-2134786-B1 DISPERSION, GEL AND EMULSIFICATION SYSTEM CRODA SINGAPORE PTE LTD (SG) 2019-07-31 EP disclosed
US-9862853-B2 Dispersion, gel and emulsification system CRODA SINGAPORE PTE LIMITED (SG) 2018-01-09 US disclosed
EP-1294812-B1 PARTICULATE METAL OXIDE CRODA INT PLC (GB) 2017-05-17 EP disclosed
EP-1631526-B1 ZINC OXIDE CRODA INT PLC (GB) 2016-08-10 EP disclosed
EP-2846762-A2 COMPOSITION Croda International PLC (GB) 2015-03-18 EP disclosed
US-20140308221-A1 POROUS AND/OR HOLLOW MATERIAL CONTAINING UV ATTENUATING NANOPARTICLES, METHOD OF PRODUCTION AND USE KOBO PRODUCTS, INC. (US) 2014-10-16 US disclosed
WO-2013167866-A2 COMPOSITION CRODA INTERNATIONAL PLC (GB) 2013-11-14 WO disclosed
US-20100150850-A1 DISPERSION, GEL AND EMULSIFICATION SYSTEM CRODA SINGAPORE PTE LIMITED (SG) 2010-06-17 US disclosed
EP-2134786-A1 DISPERSION, GEL AND EMULSIFICATION SYSTEM Croda Singapore Pte Limited (SG) 2009-12-23 EP disclosed
US-7220305-B2 Particulate metal oxide CRODA INTERNATIONAL PLC (GB) 2007-05-22 US disclosed
US-20060228310-A1 combination with titanium dioxide, used in sunscreen agents, exhibiting both effective ultraviolet radiation protection and improved transparency CRODA INTERNATIONAL PLC (GB) 2006-10-12 US disclosed
US-7101427-B2 Particulate metal oxide IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 2006-09-05 US disclosed
US-20060058444-A1 Particulate metal oxide IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 2006-03-16 US disclosed
EP-1631526-A1 ZINC OXIDE Imperial Chemical Industries PLC (GB) 2006-03-08 EP disclosed
WO-2004108599-A1 ZINC OXIDE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 2004-12-16 WO disclosed
US-20030223940-A1 Particulate metal oxide IMPERIAL CHEMICAL INDUSTRIAL PLC 2003-12-04 US disclosed
EP-1294812-A1 PARTICULATE METAL OXIDE Imperial Chemical Industries PLC (GB) 2003-03-26 EP disclosed
WO-2002000797-A1 PARTICULATE METAL OXIDE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 2002-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090004132-A1 Transfer resistant cosmetic composition with improved feel TRRAP, CUTA, MMS19 LMNA 1620/4885TSHR 2023/4885ALDH1A1 4002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.