Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13847046 | 0.84 | DEGS1 (0.32) | DEGS1 | |
| SCHEMBL13028405 | 0.82 | NPSR1 (0.32) | DEGS1 | |
| SCHEMBL2332478 | 0.82 | NPSR1 (0.32) | DEGS1 | |
| SCHEMBL25687807 | 0.82 | ADORA3 (0.41) | KMT2AOPRM1NR3C2ADORA3TSHR | |
| SCHEMBL10204249 | 0.82 | RAF1 (0.43) | OPRM1NR3C2ADORA3TSHRMC4R | |
| SCHEMBL3439404 | 0.76 | ALDH1A1 (0.42) | KMT2AOPRM1NR3C2ADORA3TSHR | |
| SCHEMBL22888217 | 0.76 | KMT2A (0.54) | KMT2ADEGS1ADORA3TSHRMC4R | |
| SCHEMBL2324988 | 0.75 | OPRM1 (0.37) | OPRM1NR3C2ADORA3TSHRMC4R | |
| SCHEMBL568385 | 0.73 | OPRM1 (0.38) | OPRM1NR3C2ADORA3TSHRMC4R | |
| SCHEMBL17411826 | 0.73 | GABRP (0.36) | DEGS1TSHRGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638896-A | ASK1 inhibitors | 比奥根MA公司 | 2021-04-09 | — | — | CN | disclosed |