Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445806 | 0.85 | ALDH1A1 (0.72) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL312754 | 0.85 | ALDH1A1 (0.72) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL28093168 | 0.82 | RAB9A (0.71) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL28556103 | 0.81 | MAPT (0.64) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL6856233 | 0.81 | NPC1 (0.58) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL128781 | 0.81 | CA1 (0.61) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL29431885 | 0.81 | CA1 (0.61) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL2318688 | 0.80 | TYK2 (0.52) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL27864944 | 0.80 | NPC1 (0.51) | HPGDALDH1A1CYP3A4MAPK1NPC1 | |
| SCHEMBL3175654 | 0.79 | NPC1 (0.56) | HPGDALDH1A1CYP3A4MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759510-A | Preparation method of methoxamine hydrochloride degradation impurities | 广东嘉博制药有限公司 | 2021-05-07 | — | — | CN | disclosed |