Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28903820 | 0.78 | CCNC (0.31) | KMT2A | |
| SCHEMBL29149648 | 0.78 | CCNC (0.33) | — | |
| SCHEMBL28563045 | 0.78 | CCNC (0.31) | — | |
| SCHEMBL29149630 | 0.75 | — | — | |
| SCHEMBL28711579 | 0.74 | ALDH1A1 (0.47) | KIF11KMT2AUSP2ALDH1A1GAA | |
| SCHEMBL26988747 | 0.72 | SCN9A (0.32) | — | |
| SCHEMBL27910465 | 0.71 | SMN1; SMN2 (0.33) | KIF11KMT2ASMN1; SMN2 | |
| SCHEMBL28544455 | 0.71 | HTR5A (0.33) | KMT2A | |
| SCHEMBL17671273 | 0.70 | HDAC3 (0.30) | — | |
| SCHEMBL28584159 | 0.69 | ALOX5AP (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638898-B | Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors | 泽农医药公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-112638898-A | Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors | 泽农医药公司 | 2021-04-09 | — | — | CN | disclosed |