Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26988747 | 0.84 | SCN9A (0.32) | — | |
| SCHEMBL28903820 | 0.81 | CCNC (0.31) | CCNCCDK8POLB | |
| SCHEMBL28563045 | 0.81 | CCNC (0.31) | CCNCCDK8 | |
| SCHEMBL28549352 | 0.78 | KIF11 (0.33) | — | |
| SCHEMBL31368718 | 0.78 | POLB (0.38) | POLBSIRT6 | |
| SCHEMBL29149630 | 0.77 | — | — | |
| SCHEMBL31368709 | 0.75 | POLB (0.47) | POLBSIRT6 | |
| SCHEMBL28544455 | 0.73 | HTR5A (0.33) | CCNCCDK8SIRT6 | |
| SCHEMBL27910465 | 0.73 | SMN1; SMN2 (0.33) | POLB | |
| SCHEMBL24895761 | 0.70 | NNMT (0.45) | SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500803-A | Amino-substituted heterocycles for the treatment of cancers with EGFR mutations | 纽威伦特公司 | 2024-02-02 | — | — | CN | disclosed |