Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 4/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | TYMP | P19971 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19583424 | 0.78 | PTGES (0.78) | PTGESMITFALOX5ALDH1A1HPGD | |
| SCHEMBL295233 | 0.75 | PTGES (0.56) | PTGESMITFALOX5ALDH1A1HPGD | |
| SCHEMBL295232 | 0.75 | PTGES (0.56) | PTGESMITFALOX5ALDH1A1HPGD | |
| SCHEMBL3000739 | 0.75 | MITF (0.59) | PTGESMITFALOX5ALDH1A1HPGD | |
| SCHEMBL1649762 | 0.75 | PTGES (0.56) | PTGESMITFALOX5ALDH1A1HPGD | |
| SCHEMBL31661103 | 0.75 | PTGES (0.56) | PTGESMITFALOX5ALDH1A1HPGD | |
| SCHEMBL6449120 | 0.75 | PTGES (0.56) | PTGESMITFALOX5ALDH1A1HPGD | |
| SCHEMBL31604207 | 0.75 | PTGES (0.56) | PTGESMITFALOX5ALDH1A1HPGD | |
| SCHEMBL21058262 | 0.75 | PTGES (0.56) | PTGESMITFALOX5ALDH1A1HPGD | |
| SCHEMBL6827276 | 0.72 | PTGES (1.00) | PTGESMITFALOX5ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995642-A | Preparation method of phosphine isocoumarin | 江汉大学 | 2020-11-27 | — | — | CN | disclosed |