Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.56 |
| ▸ | TYMP | P19971 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31604207 | 1.00 | PTGES (0.56) | PTGESTYMPMAOAKDM4EALDH1A1 | |
| SCHEMBL19583424 | 0.78 | PTGES (0.78) | PTGESTYMPKDM4EALDH1A1MAPT | |
| SCHEMBL19793345 | 0.78 | ELANE (0.53) | MAOAKDM4EALDH1A1MAPTELANE | |
| SCHEMBL27845272 | 0.78 | ELANE (0.49) | MAOAKDM4EALDH1A1MAPTELANE | |
| SCHEMBL6449120 | 0.75 | PTGES (0.56) | PTGESTYMPKDM4EALDH1A1MAPT | |
| SCHEMBL28549436 | 0.75 | PTGES (0.56) | PTGESTYMPKDM4EALDH1A1MAPT | |
| SCHEMBL3000739 | 0.75 | MITF (0.59) | PTGESTYMPKDM4EALDH1A1MAPT | |
| SCHEMBL1649762 | 0.75 | PTGES (0.56) | PTGESTYMPKDM4EALDH1A1MAPT | |
| SCHEMBL21058262 | 0.75 | PTGES (0.56) | PTGESTYMPKDM4EALDH1A1MAPT | |
| SCHEMBL31661103 | 0.75 | PTGES (0.56) | PTGESTYMPKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814669-B2 | Blood sample assay method | Abbott Rapid Diagnostics International Unlimited Company (IE) | 2023-11-14 | — | — | US | disclosed |
| US-20210332410-A1 | BLOOD SAMPLE ASSAY METHOD | Abbott Rapid Diagnostics International Unlimited Company (IE) | 2021-10-28 | — | — | US | disclosed |
| US-11085066-B2 | Blood sample assay method | AXIS-SHIELD AS (NO) | 2021-08-10 | — | — | US | disclosed |
| US-20200131560-A1 | BLOOD SAMPLE ASSAY METHOD | Abbott Rapid Diagnostics International Unlimited Company (IE) | 2020-04-30 | — | — | US | disclosed |
| EP-3122735-B1 | 3-PHENYL-7-HYDROXY-ISOCOUMARINS AS MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) INHIBITORS | THE PROVOST FELLOWS FOUND SCHOLARS AND THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIV (IE) | 2019-05-08 | — | — | EP | disclosed |
| US-20190071410-A1 | 3-Phenyl-7-Hydroxy-Isocoumarins as Macrophage Migration Inhibitory Factor (MIF) Inhibitors | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2019-03-07 | — | — | US | disclosed |
| EP-3435089-A1 | DETERMINATION OF NON-HDL CHOLESTEROL IN BLOOD | Axis-Shield AS (NO) | 2019-01-30 | — | — | EP | disclosed |
| CN-108947900-A | The method of carbon arylation tandem reaction synthesizing heterocyclic compound of the photoinduction without metal catalytic | 河南大学 | 2018-12-07 | — | — | CN | disclosed |
| EP-2751575-B1 | BLOOD SAMPLE ASSAY METHOD | AXIS SHIELD AS (NO) | 2018-09-12 | — | — | EP | disclosed |
| US-10043981-B2 | Light-emitting material, organic light-emitting device, and compound | KYULUX, INC. (JP) | 2018-08-07 | — | — | US | disclosed |
| EP-2235543-A1 | METHOD TO DETERMINE LIPIDS | Axis-Shield Asa (NO) | 2010-10-06 | — | — | EP | disclosed |
| US-20090264404-A1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-10-22 | — | — | US | disclosed |
| WO-2009081140-A1 | METHOD TO DETERMINE LIPIDS | AXIS-SHIELD ASA (NO) | 2009-07-02 | — | — | WO | disclosed |
| US-7459465-B2 | Isoquinoline compound and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-12-02 | — | — | US | disclosed |
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| US-20070161620-A1 | ISOQUINOLINE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI PHARMA CORPORATION (JP) | 2007-07-12 | — | — | US | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |
| US-RE39199-E1 | Antipsoriatic compositions, method of making, and method of using | MOADY NASEBA | 2006-07-18 | — | — | US | disclosed |
| US-5955081-A | TREATMENT OF SKIN DISORDERS WITH PLANT EXTRACTS | Z-92, INC. | 1999-09-21 | — | — | US | disclosed |
| US-4650881-A | ONE POT | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1987-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10043981-B2 | Light-emitting material, organic light-emitting device, and compound | GRK1, ARL1, NR2E3 | PTGES 2883/4885TYMP 4387/4885MAOA 2064/4885 |
| US-20090264404-A1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders | GRIN2C, GRIN2B, PMP22 | PTGES 2661/4885TYMP 3933/4885MAOA 746/4885 |
| US-20190071410-A1 | 3-Phenyl-7-Hydroxy-Isocoumarins as Macrophage Migration Inhibitory Factor (MIF) Inhibitors | MIF, CCL2, MMP12 | PTGES 193/4885TYMP 3409/4885MAOA 4106/4885 |
| US-20070161620-A1 | ISOQUINOLINE COMPOUND AND PHARMACEUTICAL USE THEREOF | NQO1, PARP1, NUDT1 | PTGES 2145/4885TYMP 631/4885MAOA 272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.