Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 15/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855591 | 0.92 | CCR2 (0.41) | CCR1CYP1A2GAACYP2D6CYP2C19 | |
| SCHEMBL2859076 | 0.89 | KEAP1 (0.42) | CCR1 | |
| SCHEMBL2854487 | 0.87 | TSHR (0.45) | CCR1MEN1KMT2ALMNAHPGD | |
| SCHEMBL2849956 | 0.85 | CCR1 (0.62) | CCR1MEN1PLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL2850732 | 0.85 | CCR1 (0.53) | CCR1MEN1PLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL2855376 | 0.85 | CCR1 (0.60) | CCR1MEN1PLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL2857366 | 0.84 | CCR1 (0.47) | CCR1 | |
| SCHEMBL2856556 | 0.84 | CCR1 (0.54) | CCR1 | |
| SCHEMBL2860247 | 0.84 | CCR1 (0.59) | CCR1 | |
| SCHEMBL2852539 | 0.83 | LMNA (0.52) | CCR1MEN1PLA2G1BCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |