Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.57 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.56 |
| ▸ | CACNB1 | Q02641 | 5/20 | 0.56 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.56 |
| ▸ | CNR1 | P21554 | 3/20 | 0.55 |
| ▸ | CNR2 | P34972 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20804660 | 0.87 | MAOB (0.61) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| SCHEMBL7054929 | 0.82 | OPRM1 (0.63) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| SCHEMBL23293370 | 0.82 | CACNA2D1 (0.51) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| SCHEMBL643105 | 0.80 | ALDH1A1 (0.55) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| SCHEMBL20804479 | 0.79 | SLC6A4 (0.52) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| SCHEMBL12508362 | 0.77 | OPRM1 (0.57) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| SCHEMBL1111708 | 0.77 | OPRM1 (0.57) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| SCHEMBL8124509 | 0.77 | OPRD1 (0.57) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| Trifluoroacetic Acid SCHEMBL26980890 | 0.76 | OPRD1 (0.56) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| Trifluoroacetic Acid SCHEMBL23293527 | 0.76 | OPRD1 (0.56) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-112585139-A | Nalidinone compounds as T cell activators | 百时美施贵宝公司 | 2021-03-30 | — | — | CN | disclosed |