SCHEMBL28554379

SCHEMBL28554379

O=P(O)(O)OOc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 4/20 0.36
INPP5A Q14642 4/20 0.36
AKT1 P31749 1/20 0.36
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
FABP3 P05413 1/20 0.35
MRGPRX4 Q96LA9 1/20 0.35
FDPS P14324 1/20 0.32
INPP5B P32019 2/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28444281 0.83 INPPL1 (0.41) INPPL1INPP5ACYP3A4MRGPRX4INPP5B
SCHEMBL258268 0.80 INPPL1 (0.54) INPPL1INPP5AAKT1CYP3A4MAPK1
SCHEMBL30023648 0.80 INPPL1 (0.54) INPPL1INPP5AAKT1CYP3A4MAPK1
SCHEMBL29148566 0.76 TDP1 (0.46) MRGPRX4TDP1
SCHEMBL28777742 0.74 SMN1; SMN2 (0.50) INPPL1INPP5AINPP5B
SCHEMBL258267 0.71 LMNA (0.36) INPPL1INPP5AAKT1CYP3A4MAPK1
SCHEMBL11449226 0.70 TSHR (0.33) INPPL1INPP5AAKT1CYP3A4MAPK1
SCHEMBL31661065 0.69 LMNA (0.35) INPPL1INPP5AAKT1CYP3A4MAPK1
SCHEMBL28200093 0.69 INPPL1 (0.33) INPPL1INPP5AAKT1CYP3A4MAPK1
SCHEMBL11126358 0.68 CYP3A4 (0.38) INPPL1INPP5AAKT1CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109155184-B Coil component 阿莫绿色技术有限公司 2021-03-12 CN disclosed