Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 5/20 | 0.48 |
| ▸ | CTSB | P07858 | 5/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | CTSV | O60911 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28556972 | 0.88 | GRN (0.45) | HPGDCTSLCTSBCTSSCTSK | |
| SCHEMBL28555760 | 0.87 | TAS1R3 (0.52) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL28554992 | 0.87 | ALDH1A1 (0.48) | HPGDCTSLCTSBCTSSCTSK | |
| SCHEMBL28555031 | 0.86 | LMNA (0.51) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL28559436 | 0.85 | HTT (0.51) | CTSBMEN1KMT2ALMNANPC1 | |
| SCHEMBL28554447 | 0.85 | CTSL (0.47) | CTSLCTSBCTSSCTSKRAB9A | |
| SCHEMBL28550625 | 0.84 | GRN (0.46) | HPGDCTSBMEN1KMT2ANPC1 | |
| SCHEMBL28549970 | 0.83 | NPSR1 (0.58) | CTSLMEN1KMT2ALMNARAB9A | |
| SCHEMBL28550547 | 0.82 | TAS1R3 (0.44) | CTSLCTSBCTSSCTSK | |
| SCHEMBL28566042 | 0.81 | TAS1R3 (0.40) | HPGDCTSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778333-B | Tetrahydrooxazolopyridino-azoxanone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2022-07-05 | — | — | CN | disclosed |
| CN-112724157-B | Dihydrooxazolo [5,4-d ] pyrrolo [1,2-a ] pyrimidin-9 (5H) -one derivatives and use thereof | 中国科学院新疆理化技术研究所 | 2022-04-19 | — | — | CN | disclosed |
| CN-112851692-B | Oxazolo [5,4-d ] pyrido [1,2-a ] pyrimidone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2022-04-08 | — | — | CN | disclosed |
| CN-112851692-A | Oxazolo [5,4-d ] pyrido [1,2-a ] pyrimidone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2021-05-28 | — | — | CN | disclosed |
| CN-112778333-A | Tetrahydrooxazolopyridino-azoxanone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2021-05-11 | — | — | CN | disclosed |
| CN-112724157-A | Dihydrooxazolo [5,4-d ] pyrrolo [1,2-a ] pyrimidin-9 (5H) -one derivatives and use thereof | 中国科学院新疆理化技术研究所 | 2021-04-30 | — | — | CN | disclosed |