Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 9/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 9/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28554643 | 0.88 | HPGD (0.54) | HPGDGPR139RAB9ACTSVCTSL | |
| SCHEMBL28559436 | 0.87 | HTT (0.51) | CTSCRAB9AHTTCTSB | |
| SCHEMBL28553331 | 0.85 | TAS1R3 (0.43) | HTTCTSVCTSLCTSBCTSS | |
| SCHEMBL28554434 | 0.84 | CTSB (0.38) | RAB9ACTSLCTSBCTSSCTSK | |
| SCHEMBL28550625 | 0.84 | GRN (0.46) | GRNSORT1HPGDGPR139RAB9A | |
| SCHEMBL28554447 | 0.81 | CTSL (0.47) | CTSCRAB9ACTSLCTSBCTSS | |
| SCHEMBL28550547 | 0.81 | TAS1R3 (0.44) | CTSLCTSBCTSSCTSK | |
| SCHEMBL28550866 | 0.81 | NPSR1 (0.41) | RAB9ARAPGEF3CTSL | |
| SCHEMBL28549384 | 0.80 | MAPT (0.45) | HPGDRAB9AHTTCTSVCTSL | |
| SCHEMBL28550888 | 0.79 | ALDH1A1 (0.48) | HPGDCTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778333-B | Tetrahydrooxazolopyridino-azoxanone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2022-07-05 | — | — | CN | disclosed |
| CN-112724157-B | Dihydrooxazolo [5,4-d ] pyrrolo [1,2-a ] pyrimidin-9 (5H) -one derivatives and use thereof | 中国科学院新疆理化技术研究所 | 2022-04-19 | — | — | CN | disclosed |
| CN-112851692-B | Oxazolo [5,4-d ] pyrido [1,2-a ] pyrimidone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2022-04-08 | — | — | CN | disclosed |
| CN-112851692-A | Oxazolo [5,4-d ] pyrido [1,2-a ] pyrimidone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2021-05-28 | — | — | CN | disclosed |
| CN-112778333-A | Tetrahydrooxazolopyridino-azoxanone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2021-05-11 | — | — | CN | disclosed |
| CN-112724157-A | Dihydrooxazolo [5,4-d ] pyrrolo [1,2-a ] pyrimidin-9 (5H) -one derivatives and use thereof | 中国科学院新疆理化技术研究所 | 2021-04-30 | — | — | CN | disclosed |