Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 3/20 | 0.38 |
| ▸ | CCR1 | P32246 | 5/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857181 | 0.92 | CCR1 (0.47) | CCR1HPGDGAALMNACYP1A2 | |
| SCHEMBL2854487 | 0.88 | TSHR (0.45) | CCR1HPGDP2RX7ALDH1A1LMNA | |
| SCHEMBL2859076 | 0.84 | KEAP1 (0.42) | CCR1ALDH1A1 | |
| SCHEMBL2856252 | 0.84 | P2RX1 (0.49) | CCR2JUNNFKB1NFKB2RELA | |
| SCHEMBL2853270 | 0.84 | CCR1 (0.51) | P2RX1TMPRSS4TACR1CCR1P2RX7 | |
| SCHEMBL2857977 | 0.83 | ALDH1A1 (0.47) | HPGDALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL2857994 | 0.83 | MTOR (0.46) | TACR1CCR1MTORMLYCDP2RX7 | |
| SCHEMBL2857073 | 0.82 | CCR1 (0.48) | CCR2TACR1CCR1ALDH1A1KDM4E | |
| SCHEMBL2855603 | 0.82 | P2RX1 (0.44) | P2RX1TMPRSS4TACR1CCR1MTOR | |
| SCHEMBL2857615 | 0.82 | MTOR (0.37) | MTORP2RX7LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |