Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855591 | 0.88 | CCR2 (0.41) | CCR1P2RX7LMNAALDH1A1HPGD | |
| SCHEMBL2857181 | 0.87 | CCR1 (0.47) | CCR1LMNAMEN1KMT2AHPGD | |
| SCHEMBL2857977 | 0.86 | ALDH1A1 (0.47) | TSHRSMN1; SMN2MAPK1TRPV1LMNA | |
| SCHEMBL2859076 | 0.85 | KEAP1 (0.42) | CCR1ALDH1A1 | |
| SCHEMBL2862714 | 0.85 | TSHR (0.46) | TSHRSMN1; SMN2CCR1MAPK1TRPV1 | |
| SCHEMBL2859307 | 0.85 | TSHR (0.46) | TSHRSMN1; SMN2CCR1MAPK1TRPV1 | |
| SCHEMBL2848180 | 0.85 | CCR1 (0.51) | TSHRCCR1WDR5LMNAMEN1 | |
| SCHEMBL2852241 | 0.84 | MAPK1 (0.53) | TSHRSMN1; SMN2CCR1MAPK1P2RX7 | |
| SCHEMBL2856260 | 0.84 | TSHR (0.46) | TSHRSMN1; SMN2CCR1MAPK1TRPV1 | |
| SCHEMBL2858209 | 0.84 | CCR1 (0.48) | TSHRSMN1; SMN2CCR1MAPK1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |