Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856156 | 0.83 | MAPT (0.58) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2850365 | 0.80 | SPR (0.53) | ALDH1A1KDM4EMALT1MAPTKMT2A | |
| SCHEMBL2852810 | 0.78 | KDM4E (0.48) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2856252 | 0.78 | P2RX1 (0.49) | TRPC3 | |
| SCHEMBL2848180 | 0.77 | CCR1 (0.51) | ALDH1A1KDM4EMALT1TRPC3KMT2A | |
| SCHEMBL2854430 | 0.77 | MAPK11 (0.47) | ALDH1A1KDM4EMAPTTRPC3KMT2A | |
| SCHEMBL2854027 | 0.77 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2852951 | 0.76 | MALT1 (0.45) | ALDH1A1KDM4EMALT1TRPC3 | |
| SCHEMBL2854118 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTTRPC3POLB | |
| SCHEMBL2855376 | 0.75 | CCR1 (0.60) | KMT2ALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |