Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 6/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NEK2 | P51955 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28558686 | 0.82 | HRH3 (0.40) | PRKCQHRH3PRKCAHTR2BFLT3 | |
| SCHEMBL28552622 | 0.81 | ALDH1A1 (0.44) | HRH3KDM4E | |
| SCHEMBL30513209 | 0.80 | MAP4K4 (0.47) | KMT2A | |
| SCHEMBL29283189 | 0.80 | KDM4E (0.57) | KDM4EKMT2A | |
| SCHEMBL29177368 | 0.78 | HRH3 (0.61) | HRH3KDM4E | |
| SCHEMBL2253999 | 0.76 | GAA (0.45) | PRKCQHRH3NEK2PIM1PIM3 | |
| SCHEMBL17506213 | 0.76 | MEN1 (0.43) | PRKCQNEK2PIM1PIM3PIM2 | |
| SCHEMBL28624613 | 0.74 | KDM4E (0.50) | HRH3KDM4E | |
| SCHEMBL28447997 | 0.74 | GPR119 (0.53) | HRH3AOC3 | |
| SCHEMBL17506349 | 0.74 | PRKCA (0.41) | PRKCQPRKCAGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214246-A | Protein kinase C inhibitors and methods of their use | 诺华股份有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-106795151-B | Protein kinase C inhibitors and methods of their use | 诺华股份有限公司 | 2021-05-07 | — | — | CN | disclosed |