Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22014873 | 0.78 | L3MBTL1 (0.33) | MAPTTP53MEN1KMT2A | |
| SCHEMBL23569180 | 0.78 | L3MBTL1 (0.33) | MAPTTP53HPGDMEN1KMT2A | |
| SCHEMBL620433 | 0.76 | THRB (0.51) | HTTLMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL25794370 | 0.76 | NLRP3 (0.42) | — | |
| SCHEMBL25033769 | 0.76 | EDNRB (0.51) | MAPT | |
| SCHEMBL25034034 | 0.76 | ALDH1A1 (0.35) | HTTLMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL1163831 | 0.73 | THRB (0.56) | HTTLMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL1163808 | 0.73 | SMN1; SMN2 (0.50) | HTTLMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL24254327 | 0.73 | HPGD (0.58) | HTTLMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL30517142 | 0.72 | CYP2D6 (0.50) | HTTSMN1; SMN2TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105890-A | Amide derivative, preparation method thereof and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-112851607-A | Amide derivative, preparation method and medical application thereof | 成都百裕制药股份有限公司 | 2021-05-28 | — | — | CN | disclosed |