SCHEMBL28559554

SCHEMBL28559554

O=C(c1ccc(N=C=S)c(N=C=S)c1)c1ccc(N=C=S)c(N=C=S)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 2/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
ALDH1A1 P00352 5/20 0.33
HPGD P15428 2/20 0.33
SRD5A2 P31213 2/20 0.33
HTT P42858 2/20 0.33
LMNA P02545 2/20 0.33
HSD17B10 Q99714 2/20 0.33
MAPT P10636 2/20 0.33
GAA P10253 2/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
PKM P14618 1/20 0.33
ABCB11 O95342 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779816 0.86 NEU3 (0.42) L3MBTL1TSHRALDH1A1SRD5A2MAPT
SCHEMBL483530 0.83 SMN1; SMN2 (0.44) TDP1CYP1A2CYP3A4CYP2C9TSHR
SCHEMBL942142 0.83 CES2 (0.38) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL29874662 0.83 SMN1; SMN2 (0.44) TDP1CYP1A2CYP3A4CYP2C9TSHR
SCHEMBL28023527 0.82 CYP3A4 (0.39) TDP1ATML3MBTL1CYP1A2CYP3A4
SCHEMBL11069154 0.77 VCAM1 (0.49) TDP1ATML3MBTL1ALDH1A1SRD5A2
SCHEMBL6660393 0.76 PTPN1 (0.50) ALDH1A1HPGDMAPTPKMSMN1; SMN2
SCHEMBL941258 0.72 P2RY6 (0.50) ALDH1A1HPGDSRD5A2HTTLMNA
SCHEMBL2899363 0.72 NEU3 (0.45) TDP1L3MBTL1CYP1A2TSHRHSD17B10
SCHEMBL10472433 0.71 TTR (0.41) TDP1L3MBTL1TSHRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109575216-B Polythiol composition for plastic optical lens SKC株式会社 2021-05-11 CN disclosed