Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEU3 | Q9UQ49 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA6 | P23280 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28559554 | 0.86 | TDP1 (0.34) | TSHRPOLBGAAMAPTL3MBTL1 | |
| SCHEMBL2899363 | 0.85 | NEU3 (0.45) | NEU3TSHRTP53CA1CA2 | |
| SCHEMBL10470163 | 0.84 | TSHR (0.53) | NEU3TSHRTP53CA1CA2 | |
| SCHEMBL3399259 | 0.84 | ALDH1A1 (0.46) | NEU3TSHRKDM4EGAAMAPT | |
| SCHEMBL3398382 | 0.84 | TSHR (0.44) | NEU3TSHRTP53CA1CA2 | |
| SCHEMBL10472433 | 0.84 | TTR (0.41) | NEU3TSHRTP53CA1CA2 | |
| SCHEMBL2919702 | 0.80 | CA1 (0.57) | TSHRCA1CA2CA12CA6 | |
| SCHEMBL6660393 | 0.77 | PTPN1 (0.50) | KDM4EPOLBMAPTSIRT1KMT2A | |
| SCHEMBL455561 | 0.74 | MIF (0.54) | TSHRTP53CA1CA2CA12 | |
| SCHEMBL3398682 | 0.73 | KDM4E (0.50) | CA1CA2CA12CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635001-B1 | SUBSTITUTED THIOUREAS AS BIFUNCTIONAL CHELATORS | CYTOGEN CORP (US) | 1997-08-20 | — | — | EP | disclosed |
| US-5585468-A | MEDICAL DIAGNOSIS; TUMOR IMAGING | CYTOGEN CORPORATION (US) | 1996-12-17 | — | — | US | disclosed |
| US-5527885-A | USEFUL FOR DELIVERING DRUGS OR RADIOISOTOPES TO TARGET ORGANS, TUMORS OR THROMBI IN VIVO | CYTOGEN CORPORATION (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0635001-A1 | SUBSTITUTED THIOUREAS AS BIFUNCTIONAL CHELATORS. | CYTOGEN CORP (US) | 1995-01-25 | — | — | EP | disclosed |
| US-5326856-A | For radioimaging of organs or tumors | CYTOGEN CORPORATION (US) | 1994-07-05 | — | — | US | disclosed |
| WO-1993021151-A1 | SUBSTITUTED THIOUREAS AS BIFUNCTIONAL CHELATORS | CYTOGEN CORPORATION (US) | 1993-10-28 | — | — | WO | disclosed |