Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.49 |
| ▸ | CTSC | P53634 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28554447 | 0.81 | CTSL (0.47) | CTSCCTSLCTSSCTSBRAB9A | |
| SCHEMBL28554598 | 0.80 | CTSC (0.39) | CTSCCTSLCTSSCTSBCYP1A2 | |
| SCHEMBL5186109 | 0.79 | CTSC (0.75) | CNR2CTSCCTSLCTSSCTSB | |
| SCHEMBL28554597 | 0.78 | CYP2C9 (0.36) | CTSCCTSLCTSSCTSK | |
| SCHEMBL3028847 | 0.77 | CTSS (0.58) | CTSCCTSLCTSSCTSBCTSK | |
| SCHEMBL28557766 | 0.77 | CTSB (0.52) | CTSCCTSLCTSSCTSBCYP1A2 | |
| SCHEMBL28544996 | 0.77 | CTSS (0.50) | CTSLCTSSMEN1KMT2ANPC1 | |
| SCHEMBL28555645 | 0.76 | HDAC3 (0.34) | CTSCCTSLCTSSCTSBMEN1 | |
| SCHEMBL3033691 | 0.75 | CTSS (0.56) | CTSCCTSLCTSSCTSBCTSK | |
| SCHEMBL28555082 | 0.75 | L3MBTL1 (0.47) | CTSLCTSSPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778333-B | Tetrahydrooxazolopyridino-azoxanone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2022-07-05 | — | — | CN | disclosed |
| CN-112724157-B | Dihydrooxazolo [5,4-d ] pyrrolo [1,2-a ] pyrimidin-9 (5H) -one derivatives and use thereof | 中国科学院新疆理化技术研究所 | 2022-04-19 | — | — | CN | disclosed |
| CN-112851692-B | Oxazolo [5,4-d ] pyrido [1,2-a ] pyrimidone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2022-04-08 | — | — | CN | disclosed |
| CN-112851692-A | Oxazolo [5,4-d ] pyrido [1,2-a ] pyrimidone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2021-05-28 | — | — | CN | disclosed |
| CN-112778333-A | Tetrahydrooxazolopyridino-azoxanone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2021-05-11 | — | — | CN | disclosed |
| CN-112724157-A | Dihydrooxazolo [5,4-d ] pyrrolo [1,2-a ] pyrimidin-9 (5H) -one derivatives and use thereof | 中国科学院新疆理化技术研究所 | 2021-04-30 | — | — | CN | disclosed |