Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.56 |
| ▸ | CTSL | P07711 | 10/20 | 0.56 |
| ▸ | CTSK | P43235 | 4/20 | 0.56 |
| ▸ | CTSB | P07858 | 7/20 | 0.53 |
| ▸ | CTSC | P53634 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3028847 | 0.90 | CTSS (0.58) | CTSSCTSLCTSKCTSBCTSC | |
| SCHEMBL3033151 | 0.84 | CTSS (0.61) | CTSSCTSLCTSKCTSB | |
| SCHEMBL4505588 | 0.84 | CTSS (0.60) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3027455 | 0.82 | CTSS (0.68) | CTSSCTSLCTSKCTSB | |
| SCHEMBL12432975 | 0.79 | CTSS (0.68) | CTSSCTSLCTSKCTSB | |
| SCHEMBL31095613 | 0.79 | CTSS (0.68) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3037914 | 0.77 | CTSS (0.63) | CTSSCTSLCTSKCTSBCTSC | |
| SCHEMBL75850 | 0.76 | CTSS (0.51) | CTSSCTSLCTSKCTSB | |
| SCHEMBL28560982 | 0.75 | CNR2 (0.49) | CTSSCTSLCTSKCTSBCTSC | |
| SCHEMBL28555645 | 0.75 | HDAC3 (0.34) | CTSSCTSLCTSKCTSBCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304419-B2 | Chemical compounds | GLAXOSMITHKLINE LLC (US) | 2012-11-06 | — | — | US | disclosed |
| US-8304419-B2 | Chemical compounds | GLAXOSMITHKLINE LLC (US) | 2012-11-06 | — | — | US | disclosed |
| US-20100216746-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100216746-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-08-26 | — | — | US | disclosed |
| US-20040267026-A1 | Process for preparing 2,4,5-trisubstituted imidazoles from N-acylated alpha-amino nitriles | ASKIN DAVID (US) | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040267026-A1 | Process for preparing 2,4,5-trisubstituted imidazoles from N-acylated alpha-amino nitriles | IL4I1, PYM1, CLIC4 | CTSS 3261/4885CTSL 3205/4885CTSK 2941/4885 |
| US-20100216746-A1 | CHEMICAL COMPOUNDS | SAMHD1, POLRMT, NUDT1 | CTSS 601/4885CTSL 1209/4885CTSK 1471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.