Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27512078 | 0.77 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL28564302 | 0.73 | MAOA (0.46) | MAPTALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL69953 | 0.70 | MAPT (0.62) | MAPTALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL70034 | 0.70 | PARP10 (0.70) | MAPTALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL10664572 | 0.69 | PARP10 (0.65) | MAPTALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL69684 | 0.69 | NSD2 (0.63) | MAPTALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL31094160 | 0.69 | MAPT (0.43) | MAPTALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL2035745 | 0.68 | NSD2 (0.74) | MAPTALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL72201 | 0.68 | MAPT (0.62) | MAPTALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL418527 | 0.68 | MAPT (0.68) | MAPTALDH1A1MEN1KMT2APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109302846-B | Indolinone compounds and their use in the treatment of fibrotic diseases | 莱斯彼维特有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-109153666-B | Indole derivatives and their use as protein kinase inhibitors | 莱斯彼维特有限公司 | 2021-07-16 | — | — | CN | disclosed |