Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisole SCHEMBL28074863 | 0.85 | TDP1 (0.44) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL15784421 | 0.80 | ALDH1A1 (0.48) | MAPTALDH1A1KMT2AHPGDALOX5 | |
| SCHEMBL2244159 | 0.79 | MAOA (0.55) | MAOAMAOBMAPTALDH1A1MEN1 | |
| SCHEMBL28563303 | 0.73 | MAPT (0.45) | MAOAMAOBMAPTALDH1A1MEN1 | |
| SCHEMBL30399202 | 0.71 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL3290858 | 0.71 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL69953 | 0.70 | MAPT (0.62) | MAPTALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL19755129 | 0.70 | KMT2A (0.50) | MAOAMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL70034 | 0.70 | PARP10 (0.70) | MAPTALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL19755113 | 0.70 | MAOA (0.47) | MAOAMAOBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867707-A | Specifically formulated compositions of nintedanib and nintedanib salts for inhalation | 艾弗林制药有限公司 | 2021-05-28 | — | — | CN | disclosed |