Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2862974 | 0.93 | KEAP1 (0.50) | KEAP1NFE2L2PTGS2CARM1BRAF | |
| SCHEMBL2856588 | 0.92 | KEAP1 (0.42) | CCR1KEAP1NFE2L2PTGS2CARM1 | |
| SCHEMBL2855716 | 0.92 | KEAP1 (0.46) | KEAP1NFE2L2SCN10ACARM1BRAF | |
| SCHEMBL2855798 | 0.92 | MAPT (0.45) | CCR1KEAP1NFE2L2PTGS2CARM1 | |
| SCHEMBL2860990 | 0.91 | KEAP1 (0.43) | CCR1KEAP1NFE2L2PTGS2SCN10A | |
| SCHEMBL2861572 | 0.91 | CA1 (0.49) | CA1CA2CA4CA7 | |
| SCHEMBL2853595 | 0.90 | LMNA (0.44) | KEAP1NFE2L2PTGS2CARM1LMNA | |
| SCHEMBL2869545 | 0.89 | KEAP1 (0.40) | CCR1KEAP1NFE2L2PTGS2CARM1 | |
| SCHEMBL2852487 | 0.89 | MAPT (0.48) | CCR1KEAP1NFE2L2PTGS2EPHX2 | |
| SCHEMBL2853458 | 0.88 | CCR1 (0.46) | CCR1SCN10ACA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |