Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852372 | 0.92 | MAPT (0.48) | CA1CA2CA12CA9CA4 | |
| SCHEMBL2850733 | 0.92 | KEAP1 (0.46) | CA1CA2CA12CA9 | |
| SCHEMBL2856585 | 0.91 | CA1 (0.44) | CA1CA2CA12CA9CA7 | |
| SCHEMBL2856385 | 0.91 | CCR1 (0.44) | CA1CA2CA4CA7 | |
| SCHEMBL2854620 | 0.90 | CA1 (0.43) | CA1CA2CA12CA9 | |
| SCHEMBL2854269 | 0.87 | RAB9A (0.46) | — | |
| SCHEMBL2852799 | 0.85 | ALDH1A1 (0.46) | — | |
| SCHEMBL2856588 | 0.84 | KEAP1 (0.42) | CA1CA2CA12CA9 | |
| SCHEMBL2862974 | 0.83 | KEAP1 (0.50) | — | |
| SCHEMBL2855798 | 0.83 | MAPT (0.45) | CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |