Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAPDH | P04406 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL19469522 | 0.84 | PPARA (0.49) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL10064132 | 0.81 | KMT2A (0.51) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL1855445 | 0.81 | LMNA (0.62) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL2733818 | 0.77 | ALDH1A1 (0.51) | LMNAGAAALDH1A1KMT2APOLB | |
| SCHEMBL2900297 | 0.76 | LMNA (0.60) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL27934725 | 0.75 | ALDH1A1 (0.46) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL4758947 | 0.75 | LMNA (0.65) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL27598271 | 0.74 | LMNA (0.59) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL7074846 | 0.74 | LMNA (0.60) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL10334579 | 0.74 | ALDH1A1 (0.49) | LMNAGAAALDH1A1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407801-B | 3, 4-methylenedioxy phenoxy fibrate- (3, 4-methylenedioxy) phenyl ester compound and application thereof in reducing blood fat | 陕西中医药大学 | 2020-12-22 | — | — | CN | disclosed |