SCHEMBL28565013

SCHEMBL28565013

O=C(CC(=O)n1ccnc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
PLOD2 O00469 2/20 0.54
CYP3A4 P08684 2/20 0.54
HPGD P15428 2/20 0.54
PLOD3 O60568 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
PLOD1 Q02809 1/20 0.54
HIF1A Q16665 1/20 0.54
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TBXAS1 P24557 1/20 0.50
KDM4E B2RXH2 1/20 0.50
MAPT P10636 1/20 0.50
ALOX15 P16050 1/20 0.50
CES1 P23141 1/20 0.50
MAPK1 P28482 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16573544 0.86 TBXAS1 (0.56) ALDH1A1PLOD2CYP3A4HPGDPLOD3
SCHEMBL6735760 0.78 ALDH1A1 (0.43) ALDH1A1TBXAS1MAPTTDP1CYP19A1
SCHEMBL1424751 0.78 CYP19A1 (0.47) CYP3A4MEN1KMT2ATBXAS1MAPT
SCHEMBL3157560 0.77 ALDH1A1 (0.48) ALDH1A1TBXAS1TDP1FAAHMGLL
SCHEMBL10613945 0.77 CYP19A1 (0.47) CYP3A4CYP1A2CYP2D6TBXAS1MAPT
Bromide SCHEMBL6985997 0.75 ALDH1A1 (0.47) ALDH1A1TBXAS1TDP1FAAHMGLL
SCHEMBL19494252 0.75 NPC1 (0.55) ALDH1A1PLOD2CYP3A4HPGDPLOD3
SCHEMBL1260766 0.74 TBXAS1 (0.50) ALDH1A1CYP3A4CYP1A2CYP2D6TBXAS1
SCHEMBL1509735 0.73 CYP19A1 (0.71) ALDH1A1TBXAS1TDP1CYP19A1L3MBTL1
SCHEMBL27857452 0.73 CYP3A4 (0.45) CYP3A4CYP1A2CYP2D6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778206-B Preparation method and application of high-absorption chrome tanning auxiliary containing ketosulfonate structure 南京工业大学 2023-01-17 CN claimed
CN-112778206-A Preparation method and application of high-absorption chrome tanning auxiliary agent containing ketosulfonate structure 南京工业大学 2021-05-11 CN claimed
CN-112778206-B Preparation method and application of high-absorption chrome tanning auxiliary containing ketosulfonate structure 南京工业大学 2023-01-17 CN disclosed
CN-112778206-A Preparation method and application of high-absorption chrome tanning auxiliary agent containing ketosulfonate structure 南京工业大学 2021-05-11 CN disclosed