Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856517 | 0.89 | MAPT (0.42) | NPY5RMAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2852552 | 0.87 | MEN1 (0.51) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL2854596 | 0.86 | TP53 (0.46) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL2848541 | 0.86 | RAB9A (0.43) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL2854758 | 0.86 | MEN1 (0.49) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL2859508 | 0.85 | CYP1A2 (0.46) | NPY5RMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2857955 | 0.85 | NPY5R (0.42) | NPY5RMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2855775 | 0.84 | P2RY1 (0.44) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL2857444 | 0.84 | ALDH1A1 (0.42) | NPY5RMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2860712 | 0.84 | MAPT (0.47) | NPY5RMAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |