Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 15/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850389 | 0.87 | NPY5R (0.40) | NPY5RMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2854497 | 0.85 | NPY5R (0.44) | NPY5RMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2852387 | 0.85 | P2RX7 (0.37) | MALT1MAPTKEAP1NFE2L2 | |
| SCHEMBL2857444 | 0.83 | ALDH1A1 (0.42) | NPY5RMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2850855 | 0.83 | KEAP1 (0.36) | NPY5RALDH1A1MALT1MAPTKEAP1 | |
| SCHEMBL2852553 | 0.80 | MALT1 (0.40) | MEN1KMT2AL3MBTL1MALT1MAPT | |
| SCHEMBL2856517 | 0.80 | MAPT (0.42) | NPY5RALDH1A1MAPT | |
| SCHEMBL2854492 | 0.78 | MAPT (0.42) | MEN1ALDH1A1KMT2AL3MBTL1MALT1 | |
| SCHEMBL2852401 | 0.78 | L3MBTL1 (0.39) | MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2856974 | 0.77 | MAPT (0.39) | MEN1KMT2AL3MBTL1MALT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |