SCHEMBL28565356

SCHEMBL28565356

C(=Cc1cccc(-c2ccccn2)c1-c1ccccn1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.48
KDM4E B2RXH2 4/20 0.42
LMNA P02545 3/20 0.42
CCR1 P32246 2/20 0.42
CCR5 P51681 2/20 0.42
CCR8 P51685 2/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
METAP1 P53582 1/20 0.42
BLM P54132 1/20 0.42
HIF1A Q16665 1/20 0.42
DOHH Q9BU89 1/20 0.42
P4HTM Q9NXG6 1/20 0.42
NFE2L2 Q16236 3/20 0.42
TRPA1 O75762 2/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
TDP1 Q9NUW8 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4165023 0.91 KDM4E (0.46) KDM1AKDM4ELMNACCR1CCR5
SCHEMBL4165025 0.91 KDM4E (0.46) KDM1AKDM4ELMNACCR1CCR5
SCHEMBL4155559 0.90 KDM1A (0.47) KDM1AKDM4ELMNACCR1CCR5
SCHEMBL2773355 0.90 KDM1A (0.47) KDM1AKDM4ELMNACCR1CCR5
SCHEMBL4155634 0.84 L3MBTL1 (0.41) KDM1AKDM4ELMNACCR1CCR5
SCHEMBL4155639 0.84 L3MBTL1 (0.41) KDM1AKDM4ELMNACCR1CCR5
SCHEMBL4159067 0.80 NFE2L2 (0.59) KDM4ELMNACYP1A2NFE2L2TRPA1
SCHEMBL4155504 0.80 LMNA (0.41) KDM1AKDM4ELMNACCR1CCR5
SCHEMBL4159062 0.80 NFE2L2 (0.59) KDM4ELMNACYP1A2NFE2L2TRPA1
SCHEMBL4155506 0.80 LMNA (0.41) KDM1AKDM4ELMNACCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107602486-B Dipyrimidyl diphenylethylene fluorescent whitening agent and preparation method and application thereof 贺州学院 2021-05-25 CN claimed
CN-107602486-B Dipyrimidyl diphenylethylene fluorescent whitening agent and preparation method and application thereof 贺州学院 2021-05-25 CN disclosed