Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4155506 | 1.00 | LMNA (0.41) | LMNASCN5ASCN9ANFE2L2PDCD1 | |
| SCHEMBL4165025 | 0.85 | KDM4E (0.46) | LMNANFE2L2KDM1AKDM4ENPC1 | |
| SCHEMBL4165023 | 0.85 | KDM4E (0.46) | LMNANFE2L2KDM1AKDM4ENPC1 | |
| SCHEMBL7646425 | 0.81 | SCN5A (0.44) | LMNASCN5ASCN9ANFE2L2KDM4E | |
| SCHEMBL28565356 | 0.80 | KDM1A (0.48) | LMNANFE2L2KDM1AKDM4ENPC1 | |
| SCHEMBL4155639 | 0.78 | L3MBTL1 (0.41) | LMNANFE2L2KDM1AKDM4ENPC1 | |
| SCHEMBL4155634 | 0.78 | L3MBTL1 (0.41) | LMNANFE2L2KDM1AKDM4ENPC1 | |
| SCHEMBL5492352 | 0.76 | NFKB1 (0.56) | NFE2L2RAB9ATRPA1NFKB1 | |
| SCHEMBL5492342 | 0.76 | NFKB1 (0.56) | NFE2L2RAB9ATRPA1NFKB1 | |
| SCHEMBL4159067 | 0.74 | NFE2L2 (0.59) | LMNANFE2L2KDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8212048-B2 | Method of producing aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-03 | — | — | US | disclosed |
| US-8212048-B2 | Method of producing aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-03 | — | — | US | disclosed |
| US-8212048-B2 | Method of producing aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-03 | — | — | US | disclosed |
| CN-101410375-B | Process for producing aromatic compound | SUMITOMO CO LTD | 2012-06-13 | — | — | CN | disclosed |
| CN-101410375-A | Process for producing aromatic compound | SUMITOMO CHEMICAL CO (JP) | 2009-04-15 | — | — | CN | disclosed |
| US-20090043096-A1 | METHOD OF PRODUCING AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-12 | — | — | US | disclosed |
| US-20090043096-A1 | METHOD OF PRODUCING AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-12 | — | — | US | disclosed |
| US-20090043096-A1 | METHOD OF PRODUCING AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043096-A1 | METHOD OF PRODUCING AROMATIC COMPOUND | AHR, CYP1A1, ARNT | LMNA 2466/4885SCN5A 3219/4885SCN9A 3039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.