Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 7/20 | 0.38 |
| ▸ | LAP3 | P28838 | 2/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14778003 | 0.89 | ALDH1A1 (0.35) | MMP1MMP2MMP3MMP8 | |
| Iodide SCHEMBL14777842 | 0.89 | ALDH1A1 (0.35) | MMP1MMP2MMP3MMP8 | |
| Bromide SCHEMBL14777926 | 0.89 | ALDH1A1 (0.35) | MMP1MMP2MMP3MMP8 | |
| SCHEMBL20707748 | 0.80 | MMP1 (0.33) | MMP1MMP2MMP3MMP8 | |
| Bromide SCHEMBL14778138 | 0.79 | ALDH1A1 (0.39) | MMP1MMP2MMP3MMP8 | |
| Iodide SCHEMBL14779246 | 0.79 | ALDH1A1 (0.39) | MMP1MMP2MMP3MMP8 | |
| Hydrochloric Acid SCHEMBL14778571 | 0.79 | ALDH1A1 (0.39) | MMP1MMP2MMP3MMP8 | |
| Phosphoric Acid SCHEMBL28355515 | 0.78 | FDPS (0.52) | FDPSLAP3GGPS1SMPD1 | |
| Phosphoric Acid SCHEMBL28883085 | 0.78 | FDPS (0.52) | FDPSLAP3GGPS1SMPD1 | |
| SCHEMBL11193257 | 0.77 | LMNA (0.38) | MMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112708106-B | Polyisocyanate composition, coating composition and coated substrate | 旭化成株式会社 | 2023-05-02 | — | — | CN | disclosed |
| CN-112708106-A | Polyisocyanate composition, coating composition and coated substrate | 旭化成株式会社 | 2021-04-27 | — | — | CN | disclosed |