Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 3/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856603 | 0.90 | KDM4E (0.40) | KDM4EPOLBGAATSHRCTNNB1 | |
| SCHEMBL15848284 | 0.90 | KDM4E (0.40) | KDM4EPOLBGAATSHRCTNNB1 | |
| SCHEMBL2856612 | 0.90 | KDM4E (0.40) | KDM4EPOLBGAATSHRCTNNB1 | |
| SCHEMBL2857199 | 0.89 | MEN1 (0.49) | KDM4EPOLBGAATSHRCTNNB1 | |
| SCHEMBL17459765 | 0.87 | NR1H2 (0.37) | KDM4EPOLBGAACTNNB1MEN1 | |
| SCHEMBL204615 | 0.84 | TSHR (0.41) | KDM4EPOLBGAATSHRCTNNB1 | |
| SCHEMBL29359688 | 0.82 | GAA (0.39) | KDM4EPOLBGAATSHRCYP1A2 | |
| SCHEMBL204614 | 0.82 | GAA (0.39) | KDM4EPOLBGAATSHRCYP1A2 | |
| SCHEMBL2107594 | 0.81 | KDM4E (0.59) | KDM4EPOLBGAACTNNB1MEN1 | |
| SCHEMBL2855939 | 0.81 | KDM4E (0.59) | KDM4EPOLBGAACTNNB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12012399-B2 | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2024-06-18 | — | — | US | disclosed |
| US-20240041028-A1 | DELIVERY SYSTEM FOR PLANT PROTECTION | OMYA INTERNATIONAL AG (CH) | 2024-02-08 | — | — | US | disclosed |
| US-11882834-B2 | Microbiocidal thiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2024-01-30 | — | — | US | disclosed |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | SYNGENTA PARTICIPATIONS AG (CH) | 2023-09-05 | — | — | US | disclosed |
| EP-3717479-B1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-07-05 | — | — | EP | disclosed |
| EP-3941898-B1 | FUNGICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| EP-3244732-B1 | USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS | OMYA INT AG (CH) | 2023-05-03 | — | — | EP | disclosed |
| US-11629129-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| US-11629138-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| EP-3692029-B1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-12 | — | — | EP | disclosed |
| US-7001903-B2 | Synergistic insecticidal mixtures | BAYER AKTIENGESELLSCHAFT (DE) | 2006-02-21 | — | — | US | disclosed |
| US-20050187215-A1 | synergistic mixture of certain previously disclosed cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-08-25 | — | — | US | disclosed |
| US-6893651-B1 | Synergistic combination of cyclic ketoenol with agonists or antagonists of nicotinic acetylcholine receptors; protecting plants | BAYER AKTIENGESELLSCHAFT (DE) | 2005-05-17 | — | — | US | disclosed |
| US-6846777-B2 | Synergistic biocidal composition | THOR GMBH (DE) | 2005-01-25 | — | — | US | disclosed |
| US-20040127520-A1 | Synergistic insecticidal mixtures | DOW AGROSCIENCES LLC | 2004-07-01 | — | — | US | disclosed |
| US-6686387-B2 | SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS; PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| US-20030199490-A1 | Synergistic biocidal composition | THOR GMBH (DE) | 2003-10-23 | — | — | US | disclosed |
| US-20030092641-A1 | Synergistic insecticidal mixtures | DOW AGROSCIENCES LLC | 2003-05-15 | — | — | US | disclosed |
| US-6444667-B1 | OF SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS FOR PROTECTING PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-5466693-A | FOE USE IN THE CULTIVATION OF RICE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092641-A1 | Synergistic insecticidal mixtures | CHRM3, ACHE, CHRM2 | KDM4E 3852/4885POLB 4880/4885GAA 4625/4885 |
| US-20040127520-A1 | Synergistic insecticidal mixtures | CHRM3, ACHE, CHRM2 | KDM4E 3852/4885POLB 4880/4885GAA 4625/4885 |
| US-11882834-B2 | Microbiocidal thiazole derivatives | MSR1, TLR1, IFNG | KDM4E 3260/4885POLB 3655/4885GAA 1215/4885 |
| US-12012399-B2 | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives | TLR1, TLR5, IDO1 | KDM4E 2885/4885POLB 2340/4885GAA 322/4885 |
| US-20050187215-A1 | synergistic mixture of certain previously disclosed cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors | CHRNG, CHRM3, CHRNE | KDM4E 1928/4885POLB 4609/4885GAA 2385/4885 |
| US-11629138-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, FPR1 | KDM4E 2969/4885POLB 3534/4885GAA 2152/4885 |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | PHF20, FUCA1, ZP1 | KDM4E 4050/4885POLB 4375/4885GAA 920/4885 |
| US-11629129-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, MSR1 | KDM4E 3192/4885POLB 3215/4885GAA 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.