Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | FES | P07332 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.37 |
| ▸ | FER | P16591 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13917369 | 0.87 | HSD17B1 (0.48) | METAP2HSD17B1HSD17B2IDO1PLK4 | |
| SCHEMBL1925054 | 0.83 | IDO1 (0.53) | METAP2HSD17B1HSD17B2IDO1RAB9A | |
| SCHEMBL4905641 | 0.81 | HSD17B1 (0.62) | METAP2HSD17B1HSD17B2MAP4K4IRAK4 | |
| SCHEMBL27614819 | 0.81 | IDO1 (0.51) | METAP2HSD17B1HSD17B2IDO1RAB9A | |
| SCHEMBL1926737 | 0.81 | IDO1 (0.51) | METAP2HSD17B1HSD17B2IDO1RAB9A | |
| SCHEMBL2482041 | 0.80 | HSD17B1 (0.47) | METAP2HSD17B1HSD17B2IDO1PLK4 | |
| SCHEMBL17776911 | 0.79 | CYP3A4 (0.54) | METAP2HSD17B1HSD17B2IDO1CHRNB4 | |
| SCHEMBL31689000 | 0.79 | KDM1A (0.54) | HSD17B1HSD17B2IDO1MAP4K4KDM1A | |
| SCHEMBL15747739 | 0.79 | HPGDS (0.56) | HSD17B1HSD17B2IDO1MAP4K4HPGDS | |
| SCHEMBL969090 | 0.79 | MAP4K4 (0.50) | METAP2HSD17B1HSD17B2MAP4K4MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942541-B | Fluorenocarbazole derivative and preparation method and application thereof | 武汉尚赛光电科技有限公司 | 2021-06-01 | — | — | CN | disclosed |