Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | PNMT | P11086 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29576846 | 0.80 | CREBBP (0.47) | BRD4MEN1KMT2ACREBBPEP300 | |
| SCHEMBL27740237 | 0.76 | CMA1 (0.34) | ADRA2APNMTADRA2BADRA2CBRD4 | |
| SCHEMBL27841487 | 0.73 | TGM2 (0.36) | BRD4MEN1KMT2ACMA1AHR | |
| SCHEMBL27515354 | 0.73 | BRD4 (0.34) | ADRA2APNMTADRA2BADRA2CBRD4 | |
| SCHEMBL27465296 | 0.72 | BRD4 (0.40) | BRD4MEN1KMT2AALOX5LMNA | |
| SCHEMBL22471500 | 0.71 | BRD4 (0.38) | ADRA2APNMTADRA2BADRA2CBRD4 | |
| SCHEMBL28566657 | 0.71 | CREBBP (0.62) | BRD4ALOX5CREBBP | |
| SCHEMBL23063003 | 0.70 | BRD4 (0.42) | ADRA2APNMTADRA2BADRA2CBRD4 | |
| SCHEMBL16722791 | 0.70 | PNMT (0.42) | ADRA2APNMTADRA2BADRA2CBRD4 | |
| SCHEMBL24290488 | 0.70 | PNMT (0.42) | ADRA2APNMTADRA2BADRA2CBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207493-B | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-115583947-A | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-01-10 | — | — | CN | disclosed |