SCHEMBL28566705

SCHEMBL28566705

O=C(c1ccc(F)cc1)c1c(F)cccc1F

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.56
CES1 P23141 4/20 0.56
LTA4H P09960 1/20 0.52
GAA P10253 1/20 0.49
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
BCL2L1 Q07817 1/20 0.45
BAD Q92934 1/20 0.45
LMNA P02545 2/20 0.45
HPGD P15428 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
ALOX12 P18054 1/20 0.45
ATM Q13315 1/20 0.45
ALDH1A1 P00352 2/20 0.44
ALPG P10696 1/20 0.44
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1420986 0.84 ALDH1A1 (0.59) CES2CES1GAAMEN1KMT2A
SCHEMBL27653331 0.83 CES2 (0.70) CES2CES1GAAMEN1KMT2A
SCHEMBL1631868 0.83 ALDH1A1 (0.60) CES2CES1GAAMEN1KMT2A
SCHEMBL27876858 0.83 CES2 (0.52) CES2CES1CA1CA2MEN1
SCHEMBL238259 0.80 LTA4H (0.73) CES2CES1LTA4HCA1CA2
SCHEMBL1736339 0.80 LTA4H (0.73) CES2CES1LTA4HCA1CA2
SCHEMBL8572071 0.80 LTA4H (0.73) CES2CES1LTA4HCA1CA2
SCHEMBL29377967 0.78 CES2 (0.56) CES2CES1LTA4HGAAMEN1
SCHEMBL6096428 0.78 KDM4E (0.49) CES2CES1LTA4HCA1CA2
SCHEMBL609880 0.78 GAA (0.54) CES2CES1LTA4HGAACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069931-B Hyperbranched fluorenyl photosensitive polyaryletherketone precursor, composition, film and preparation method thereof 大连理工大学 2024-02-23 CN claimed
CN-117069931-A Hyperbranched fluorenyl photosensitive polyaryletherketone precursor, composition, film and preparation method thereof 大连理工大学 2023-11-17 CN claimed
CN-116789954-A Acrylate-based photosensitive hyperbranched polyaryletherketone as well as preparation method and application thereof 大连理工大学 2023-09-22 CN claimed
CN-112920520-A Heat-insulating nano plastic for floor and preparation method thereof 刘赛萍 2021-06-08 CN claimed
CN-117069931-B Hyperbranched fluorenyl photosensitive polyaryletherketone precursor, composition, film and preparation method thereof 大连理工大学 2024-02-23 CN disclosed
CN-117069931-B Hyperbranched fluorenyl photosensitive polyaryletherketone precursor, composition, film and preparation method thereof 大连理工大学 2024-02-23 CN disclosed
CN-117069931-A Hyperbranched fluorenyl photosensitive polyaryletherketone precursor, composition, film and preparation method thereof 大连理工大学 2023-11-17 CN disclosed
CN-117069931-A Hyperbranched fluorenyl photosensitive polyaryletherketone precursor, composition, film and preparation method thereof 大连理工大学 2023-11-17 CN disclosed
CN-116789954-A Acrylate-based photosensitive hyperbranched polyaryletherketone as well as preparation method and application thereof 大连理工大学 2023-09-22 CN disclosed
CN-112920520-A Heat-insulating nano plastic for floor and preparation method thereof 刘赛萍 2021-06-08 CN disclosed
CN-110042487-B Quantum dot/polyaryletherketone nanocomposite and preparation method thereof 吉林大学 2021-04-06 CN disclosed