Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10954021 | 0.87 | KDM4E (0.43) | KDM4ELTA4HCES2CES1KMT2A | |
| SCHEMBL10480661 | 0.86 | KDM4E (0.60) | KDM4EKMT2AMEN1HTTNPC1 | |
| SCHEMBL9726573 | 0.82 | KMT2A (0.57) | KDM4ELTA4HCES2CES1KMT2A | |
| SCHEMBL806809 | 0.82 | LTA4H (0.47) | KDM4ELTA4HCES2CES1KMT2A | |
| SCHEMBL3039645 | 0.80 | ALDH1A1 (0.59) | CES2CES1KMT2AMEN1TSHR | |
| SCHEMBL1584375 | 0.80 | KMT2A (0.56) | KDM4ELTA4HKMT2AMEN1HTT | |
| SCHEMBL11612501 | 0.79 | ALDH1A1 (0.48) | KDM4EKMT2AMEN1TSHRCA1 | |
| SCHEMBL29983601 | 0.79 | LTA4H (0.70) | KDM4ELTA4HCES2CES1HTT | |
| SCHEMBL30632245 | 0.79 | LTA4H (0.70) | KDM4ELTA4HCES2CES1HTT | |
| SCHEMBL28566705 | 0.78 | CES2 (0.56) | KDM4ELTA4HCES2CES1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140154610-A1 | AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND USES THEREOF | JSR CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| US-20140154610-A1 | AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND USES THEREOF | JSR CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2738194-A1 | AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND APPLICATION THEREOF | JSR Corporation (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-7119215-B2 | Production method of citalopram, intermediate therefor and production method of the intermediate | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2006-10-10 | — | — | US | disclosed |
| US-6946564-B2 | Production method of an intermediate for citalopram | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-09-20 | — | — | US | disclosed |
| US-20040230066-A1 | Production method of citalopram, intermediate therefor and production method of the intermediate | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2004-11-18 | — | — | US | disclosed |
| US-20040138497-A1 | Production method of citalopram, intermediate therefor and production method of the intermediate | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1125907-B1 | Intermediates for the production of citalopram | SUMIKA FINE CHEMICALS CO LTD (JP) | 2004-07-14 | — | — | EP | disclosed |
| EP-1428813-A1 | Production method of citalopram and intermediates therefor | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6458975-B1 | 1-(ALPHA-HYDROXY-P-FLUOROBENZYL)-2,4-DIMETHYLBENZENE INTERMEDIATE; PRODUCTION OF 4-(P-FLUOROBENZOYL)ISOPHTHALIC ACID AND USE AS INTERMEDIATE | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-10-01 | — | — | US | disclosed |
| US-6433196-B1 | REACTING 3-(DIMETHYLAMINO)PROPYL CHLORIDE IN PRESENCE OF 1,3-DIMETHYL-2-IMIDAZOLIDINONE AND, OR TETRAMETHYLETHYLENEDIAMINE; REDUCTION, CYCLIZATION; ANTIDEPRESSANTS | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-08-13 | — | — | US | disclosed |
| US-20020095051-A1 | Production method of citalopram, intermediate therefor and production method of the intermediate | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-07-18 | — | — | US | disclosed |
| US-20020062040-A1 | PRODUCTION METHOD OF CITALOPRAM, INTERMMEDIATE THEREFOR AND PRODUCTION METHOD OF THE INTERMEDIATE | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-05-23 | — | — | US | disclosed |
| EP-1125907-A2 | Intermediates for the production of citalopram | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2001-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020095051-A1 | Production method of citalopram, intermediate therefor and production method of the intermediate | INMT, FAR1, CYP51A1 | KDM4E 2317/4885LTA4H 3525/4885CES2 911/4885 |
| US-20040138497-A1 | Production method of citalopram, intermediate therefor and production method of the intermediate | INMT, FAR1, CYP51A1 | KDM4E 2317/4885LTA4H 3525/4885CES2 911/4885 |
| US-20020062040-A1 | PRODUCTION METHOD OF CITALOPRAM, INTERMMEDIATE THEREFOR AND PRODUCTION METHOD OF THE INTERMEDIATE | INMT, IMPDH1, HSD17B11 | KDM4E 2934/4885LTA4H 2915/4885CES2 570/4885 |
| US-20040230066-A1 | Production method of citalopram, intermediate therefor and production method of the intermediate | INMT, FAR1, CYP51A1 | KDM4E 2317/4885LTA4H 3525/4885CES2 911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.