Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571861 | 0.92 | ALDH1A1 (0.45) | RAB9ANPC1TSHRNPSR1ALDH1A1 | |
| SCHEMBL28570400 | 0.91 | RAB9A (0.43) | RAB9ANPC1RXRARXRBRXRG | |
| SCHEMBL28913498 | 0.88 | GRM5 (0.40) | RAB9ANPC1RXRARXRBRXRG | |
| SCHEMBL28570091 | 0.86 | TUBB4A (0.43) | RAB9ANPC1RXRARXRBRXRG | |
| SCHEMBL28570311 | 0.85 | RXRA (0.39) | RAB9ANPC1RXRARXRBRXRG | |
| SCHEMBL28567415 | 0.84 | MAPT (0.52) | RAB9ANPC1HPGDTSHRNPSR1 | |
| SCHEMBL28563782 | 0.79 | HCRTR1 (0.43) | RAB9ANPC1RXRARXRBRXRG | |
| SCHEMBL28573112 | 0.74 | HDAC1 (0.46) | — | |
| SCHEMBL28564284 | 0.73 | MAPT (0.52) | RAB9ANPC1HPGDTSHRNPSR1 | |
| SCHEMBL28253538 | 0.73 | ROCK1 (0.45) | RAB9ANR1H4HPGDTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794460-B | 1,2, 4-oxadiazole-3, 4-dihydroquinoline compound and preparation method and application thereof | 贵州医科大学 | 2021-05-28 | — | — | CN | disclosed |