Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28564284 | 0.87 | MAPT (0.52) | MAPTTHRBGAAALDH1A1MEN1 | |
| SCHEMBL28567359 | 0.84 | RAB9A (0.42) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL28570311 | 0.84 | RXRA (0.39) | MAPTTHRBGAAALDH1A1MEN1 | |
| SCHEMBL28571861 | 0.84 | ALDH1A1 (0.45) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL28570400 | 0.83 | RAB9A (0.43) | MAPTGAAKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL28913498 | 0.82 | GRM5 (0.40) | MAPTGAAMEN1KMT2ATSHR | |
| SCHEMBL28570091 | 0.80 | TUBB4A (0.43) | MAPTTHRBGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL28567263 | 0.79 | MAPT (0.56) | MAPTTHRBGAAALDH1A1MEN1 | |
| SCHEMBL28563782 | 0.76 | HCRTR1 (0.43) | MAPTALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL20116597 | 0.67 | MAPT (0.67) | MAPTTHRBGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794460-B | 1,2, 4-oxadiazole-3, 4-dihydroquinoline compound and preparation method and application thereof | 贵州医科大学 | 2021-05-28 | — | — | CN | disclosed |